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HOME-CAGE MONITORING

Continuous Monitoring of Digital Biomarkers in Group-housed Mice

The UID Mouse Matrix was developed to address the challenges researchers currently face when evaluating temperature and activity in socially-housed mice. This novel RFID-enabled system allows for continuous and remote monitoring of digital biomarkers, temperature and activity, for one or multiple mice in their home-cage environment.

Allentown + UID Identification Solutions
Our Story

Allentown and UID Partnership

Digital technology in the home cage is the future but in the present there has yet to be one solution that fits all research needs. There is no defined consensus among researchers on the parameters that must be monitored or how they will interpret an exponentially greater amount of data. Nor do they know exactly what their budget will allow them to pursue. Current solutions require a very large per-cage-slot investment with little flexibility, a tremendous learning curve and very little practical results. During this exciting phase of solution evolution Allentown and UID provide a practical approach — a proven home cage monitoring solution in a scalable framework to fit all needs and budgets.

The system can monitor group-housed mice in a completely undisturbed setting.

Valuable research data can be collected automatically in real-time (24/7), even during inactivity phases. In addition to removing experimenter bias, the UID Mouse Matrix can help improve study outcomes by permitting frequent and accurate measurements of progressive behavioral and physiological changes over time in the same animal.

Integration of UID Mouse Matrix Technology with Allentown's state-of-the-art rodent housing systems enables high throughput data collection and remote monitoring capabilities from high-density IVC rack systems.

Convenient and Easy to Use
The UID Mouse Matrix enables automatic, continuous, and remote monitoring of temperature and activity for group-housed mice while in their home-cage environment and without researcher interference.

Insert
Microchip

Simply insert the miniature microchip in the animals, and place them back in their cage. The UID Temperature-sensing microchip provides mouse tracking capabilities and reliable temperature measurements with unmatched accuracy to ±0.1°C.

Place
Matrix

Place the UID Mouse Matrix reader under the cage for continuous (24/7) and undisturbed tracking of the animals' temperature and activity. The Matrix reader actively polls its antennae (plate zones) to scan the cage for the presence of any microchip within range. Once detected, the microchip activates and sends relevant data (Animal ID, Temperature, Location, Time/Date) to the data collection software. Zone transitioning is done in rapid succession with timing adjusted by the user's specifications.

Collect
Data

The UID Matrix Software collects and records the data from the Matrix system(s) as often as every 200 milliseconds. The program automatically captures physiological and behavioral biomarkers in real-time (24/7), and these data can be accessed remotely or stored for further analysis.

STRATEGIC ALLIANCE WITH UID
Partnership

Better Together

Allentown partnered with Unified Information Devices (UID), the leading provider of radio-frequency identification (RFID) solutions that empower researchers to generate higher quality data faster, accurately and consistently. UID Identification Solutions combines advanced RFID technology with novel software to facilitate the identification and tracking of research animals and other laboratory items. Allentown/UID range of products help automate data collection, streamline processes and improve workflow efficiency.

Collect temperature and activity data from your mice directly from their home cage environment, rather than moving them to a foreign setting for evaluation.
  • Undisturbed rodent behavior
  • Evaluation of physiological and behavioral biomarkers
  • Accurate measurement of progressive behavioral changes
  • Reduce errors inherent in manual data entry
  • Eliminate experimenter bias
  • Increase accuracy, reproducibility and objectivity
  • Reduce animal handling and stress
  • Non-invasive temperature monitoring
  • Undisturbed monitoring of mouse activity
  • Alerts for critical health indicators
What's Inside

Matrix System Components

Create your own smart cage system and start monitoring digital biomarkers from your study animals in their home-cage environment, and without disturbing them!
Benefits
REAL-TIME MONITORING OF DIGITAL BIOMARKERS (TEMPERATURE AND ACTIVITY)
REMOTE MONITORING OF GROUP-HOUSED MICE OVER LONG PERIODS
ACCURATE TRACKING OF INDIVIDUAL ANIMALS WITHIN A GROUP
EVALUATE RODENT SOCIAL INTERACTIONS AND HOME-CAGE BEHAVIOR WITHOUT HUMAN INTERFERENCE
OBJECTIVE MONITORING OF ANIMAL BEHAVIOR DURING INACTIVITY PHASES
DETECT EARLY DISEASE ONSET AND MEASURE DISEASE PROGRESSION NON-INVASIVELY
ACCURATE MEASUREMENT OF PROGRESSIVE BEHAVIORAL CHANGES IN THE SAME ANIMAL
IMPROVE ANIMAL WELFARE BY REDUCING ANIMAL HANDLING AND STRESS
Features
HIGH FREQUENCY READOUT - MULTIPLE ANTENNAS CAPTURE AND REPORT DATA AS FAST AS EVERY 100 MILLISECONDS
EIGHT-ZONE READER PLATE CONFIGURATION
STAND ALONE SYSTEM OR NETWORKED FOR MULTIPLE CAGES ON A RACK
IMMEDIATE ACCESS TO DATA OR EXPORTED TO EXCEL FOR FURTHER ANALYSIS
INTUITIVE SOFTWARE FOR ENHANCED USER EXPERIENCE
ALERTS FOR CRITICAL INDICATORS OR ANIMAL HEALTH AND WELFARE
REAL-TIME CENSUS FOR ALL INDIVIDUAL ANIMALS
SINGLE WATERPROOF CONNECTION FOR POWER AND COMMUNICATION
Software

Mouse Matrix Analytics

Digital Content

The difference is in the details. Take a closer look.

Allentown solutions are not only crafted to perfection, they are also meticulously documented to provide users with all of the information needed to maximize their value. Take a closer look by reviewing the materials below.